The National Department of Health has extracted the key interventions that will form the basis for this strategy from the WHO and OIE recommendations. The development and implementation of anational AMR strategy that complements international efforts is a major step towards containment of the growing threat of AMR in human and animal health. Global partnerships need to be strengthened because the responsibility for reducing resistance is a shared one. This responsibility is not only limited to the health care sector, but calls for collaborative action in all sectors - human, animal and agriculture. The AMR strategy will affect South Africa's response to this looming threat. We already have the tools and expertise to make a difference, now all we need is to work togethertoward a better future.