The challenge that PMTCT is currently facing is an increasing number of babies who acquire HIV infection during the postnatal period. To address this challenge, the guidelines provide guidance on the following: Strengthening antenatal and postnatal care for both HIV negative and positive mothers,the introduction of a dolutegravir-based ART regimen which is more efficacious in reducing the risks of transmission of HIV and promoting integrated management of the mother-baby pair by aligning PMTCT interventions with BANC visits during antenatal period and EPI visits during postnatal period. These guidelines provide a framework for a service benefits package steering us towards the implementation of NHI.